Associate Software Engineer
Mayo ClinicRole Overview
Mayo Clinic is hiring a entry-level Associate Software Engineer. This is a full-time hybrid role, based in Rochester. Part of Mayo Clinic's Backend hiring. Full responsibilities, required qualifications, and the apply link are listed in the description below.
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Job Description
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
Responsibilities
Mayo Clinic Genomics and Emerging Systems Unit is seeking an Associate Software Engineer to aid in the design, development, and maintenance of robust .NET-based back-end services supporting a broad portfolio of genomics and clinical applications. These systems operate across on-premises environments and modern cloud platforms, including Azure and Google Cloud Platform (GCP), and integrate with distributed services through secure APIs and web services.
The Associate Software Engineer will work under the guidance of more senior developers to build and optimize services that handle complex genomic workflows, large-scale clinical datasets, and high-throughput data processing. This includes ensuring that all services meet strict performance, reliability, and accuracy requirements, scale effectively as data volumes grow, and remain resilient within hybrid cloud ecosystems.
The role collaborates closely with Senior Developers, Product Owners, Product Managers, Architects, and cross-functional engineering partners to translate requirements into well-architected, maintainable code. Responsibilities include designing and implementing services aligned to enterprise architecture, including cloud-ready APIs, data integration pipelines, and secure interoperability layers for genomic systems.
The engineer participates in Agile and DevOps practices using GitHub, Azure DevOps (ADO), Azure Pipelines, and CI/CD frameworks. Work may include deployment automation and configuration management using tools such as ARM/Bicep, Terraform, Cloud Build, or Azure Pipelines, supporting both on-prem and cloud-hosted applications. Development efforts leverage modern .NET technologies, cloud-native patterns, API-first design, and secure coding practices. Responsibilities also include maintaining comprehensive technical documentation, contributing to code reviews, and participating in expert-level troubleshooting through log analysis, root cause evaluation, and data/system investigation.
This position requires effective communication with peers, leaders, and clinical partners across the organization. The engineer will continue to build knowledge of genomics workflows, organizational processes, and customer needs while performing a range of technical assignments with moderate guidance and increasing autonomy. The role includes providing 24/7 on-call support.
Qualifications
Bachelor's degree in Computer Science/Engineering or related field; Or an Associate’s degree in Computer Science/Engineering or related field with 1 year of related experience; Or a high school diploma plus 4 years of experience. Completion of a Mayo internship may fulfill the requirement for 1 year of experience. Will consider a bachelor's degree in an unrelated field if accompanied by professional retraining certification. Must possess a strong technical aptitude for designing and implementing software solutions.
· Have working knowledge and experience of Software Engineering coding applications or services in a high-level language (C, C++, Golang, Java, C# etc.).
· Demonstrated problem solving and time management skills.
· Possesses strong technical aptitude for designing and implementing software solutions.
· Experience with modern application development frameworks
· Knowledge of professional software engineering practices & best practices for the full software development life cycle, including coding standards, code reviews, source control management, build processes, testing, and operations.
· Hands-on technical expertise, excellent verbal and written communication skills.
· Experience with Agile software development techniques.
Preferred qualifications
- Ability to use a wide variety of open-source technologies and cloud-based services.
- Experience developing applications in hybrid environments, including on-premises systems, Azure, and Google Cloud Platform (GCP).
- Experience in databases, analytics, big data systems or business intelligence products.
- Experience developing software for healthcare related industries.
- Familiarity with building and integrating RESTful APIs, microservices, and web services using .NET technologies.
- Knowledge of DevOps pipelines and CI/CD using Azure DevOps, GitHub Actions, or Azure Pipelines.
- Utilization of AI coding tool such as GitHub CoPilot, Gemini, Claude.
- Experience with relational and NoSQL databases, analytics platforms, big-data processing, or enterprise data pipelines.
- Background in developing high-performance, scalable, and highly available distributed systems.
During the selection process you may participate in an OnDemand (pre-recorded) interview that you can complete at your convenience. During the OnDemand interview, a question will appear on your screen, and you will have time to consider each question before responding. You will have the opportunity to re-record your answer to each question - Mayo Clinic will only see the final recording. The complete interview will be reviewed by a Mayo Clinic staff member, and you will be notified of next steps.
This vacancy is not eligible for sponsorship/we will not sponsor or transfer visas for this position. Mayo Clinic DOES NOT participate in the F-1 STEM OPT extension program.
Exemption Status
Exempt
Compensation Detail
$88,358.40 - $123,780.80 / year
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
Monday-Friday; 8:00am-5:00pm CST The role includes providing 24/7 on-call support.
Weekend Schedule
The role includes providing 24/7 on-call support.
International Assignment
No
Site Description
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is.
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the 'EOE is the Law'. Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter
Jackie Mckay
Frequently Asked Questions
How do I apply for the Associate Software Engineer position at Mayo Clinic?
Use the Apply button above to submit your application directly to Mayo Clinic. Most applications take less than 5 minutes if your resume and contact details are ready, and you'll be routed to the employer's official application system to finish.
Is the Associate Software Engineer role at Mayo Clinic remote or in-office?
This is a hybrid role based in Rochester. Expect a mix of in-office and remote days, with the specific cadence set by the hiring manager.
What does a Associate Software Engineer at Mayo Clinic earn?
Mayo Clinic has not disclosed a salary range in this posting. Many employers share specifics later in the interview process; you can also ask during a recruiter screen if compensation transparency is important to you.
When was the Associate Software Engineer role at Mayo Clinic posted?
This role was posted on April 29, 2026 (51 days ago). It's still listed as actively hiring; we re-confirm openings against the source system multiple times per day and remove closed roles.
Is the Associate Software Engineer role at Mayo Clinic entry-level?
Yes. This is an entry-level position. Strong candidates typically have 0-2 years of relevant work experience, internships, or significant project work. Read the full description for any specific qualification requirements Mayo Clinic has listed.
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