Job Title Analytical Workflow Implementation & Operationalization Specialist

Engagement Type Contract / Staff Augmentation — Full-Time Equivalent

Location GSK Upper Providence, PA (On-Site — 5 days/week preferred; hybrid negotiable)

Duration July 20, 2026 – June 30, 2027 (12 months across 3 milestone phases)

Reports To Amy Gibble, Analytical Chemistry Department, GSK Upper Providence

Role Overvie

wGSK is implementing the Bradshaw PTB platform at its Upper Providence site — an automated "design–make–test–analyze" cycle for small molecule drug discovery that integrates analytical instrumentation, purification systems, automation, and digital data workflows. The Analytical Workflow Implementation and Operationalization Specialist will serve as the primary execution resource supporting this implementation from initial planning through full operationalization across three milestone phases. The role is highly cross-functional, requiring close collaboration with GSK's Analytical Chemistry, Predictive Synthesis, Automation, Informatics, Engineering, and Discovery Chemistry teams

.

Key Responsibiliti

es

Milestone 1 — Analytical Workflow Implementation (July–December 20

26)

• Lead instrumentation readiness assessments for approximately 8 LCMS systems, 5 purification systems, and 1–2 RapidFire platforms (Waters, Agilent, Labma

n).

• Coordinate and participate in Factory Acceptance Testing (FAT) and Site Acceptance Testing (SAT) activities with analytical and automation vendo

rs.

• Develop and execute workflow planning activities for predictive synthesis and nanoscale analytical workflo

ws.

• Author or co-author Milestone 1 qualification documentation including Design Summary Reports (DSR), URS, DQ, FMEA, and Leveraging Reports in collaboration with G

SK.

• Participate in recurring project governance and implementation review meetings with GSK stakeholde

rs.

Milestone 2 — Purification and Reformatting Design Studies (January–March 2

027)

• Deliver purification and reformatting design studies defining analytical requirements and workflow specificati

ons.

• Establish implementation readiness activities for future Bradshaw purification and reformatting capabilit

ies.

• Author supporting qualification documents (DSR, FMEA, URS, DQ, Leveraging Report) for Milestone 2 sc

ope.

• Support data integration activities ensuring seamless data flow between Analytical Chemistry, Automation, and Informatics te

ams.

Milestone 3 — Workflow Refinement and Operationalization (April–June

2027)

• Refine and optimize purification and reformatting workflows based on implementation learn

ings.

• Define final implementation specifications and complete analytical risk assessm

ents.

• Establish startup readiness criteria and execute stabilization and troubleshooting activi

ties.

• Complete all Milestone 3 qualification documentation and obtain GSK stakeholder appr

oval.

• Conduct knowledge transfer and develop operational training materials for GSK s

taff.

Ongoing Across All

Phases

• Manage vendor coordination and communication with Waters, Agilent, and Labman representatives throughout the engag

ement.

• Maintain project planning and tracking documentation; ensure milestones are on track and flag risks

early.

• Develop documentation templates collaboratively with GSK where templates do not yet

exist.

• Support workflow scalability assessments and document readiness for future workflow expa

nsion.

Education Requi

rements

• Bachelor's degree (required) in Analytical Chemistry, Biochemistry, Chemical Engineering, Pharmaceutical Sciences, or a related scientific disc

ipline.

• Master's degree (preferred) in a relevant scientific or engineering disc

ipline.

• PhD (a plus) — not required; the role prioritizes hands-on implementation experience over academic crede

ntials.

Technical Skills

RequiredAnalytical Instrum

entation

• Hands-on experience operating LCMS systems (Waters and/or Agilent platforms strongly pre

ferred).

• Experience with preparative purification systems and/or RapidFire mass spectrometry pl

atforms.

• Ability to perform basic instrument troubleshooting; escalation of complex technical issues to

vendors.

Lab Automation and Workflow In

tegration

• Demonstrated experience with laboratory automation platforms and integrated high-throughput w

orkflows.

• Familiarity with automated "design–make–test–analyze" cycles or similar high-throughput discovery envi

ronments.

• Experience working in environments where analytical systems are connected to informatics and data management p

latforms.

FAT/SAT and Com

missioning

• Experience participating in or coordinating Factory Acceptance Testing (FAT) and Site Acceptance Testing (SAT) activities for laboratory instru

mentation.

• Ability to review vendor-generated documentation and assess readiness against defined acceptance

criteria.

Do

cumentation

• Ability to author GxP-aligned qualification documents including URS, DQ, DSR, FMEA, and Leveragi

ng Reports.

• Experience developing documentation in evolving, first-time-implementation environments where templates are being built colla

boratively.

• Familiarity with pharmaceutical documentation standards (ALCOA+, data integrity, controlled document m

anagement).

Soft Ski

lls Required

• Cross-functional collaboration: Comfortable working with multiple internal teams simultaneously — Analytical Chemistry, Predictive Synthesis, Automation, Informatics, Engineering, and Discover

y Chemistry.

• Organizational skills: Ability to manage multiple workstreams, track deliverables, and maintain project momentum without being directly managed

day-to-day.

• Adaptability: Comfortable operating in a project where processes and requirements are being defined in real time; not reliant on fully established procedures before ta

king action.

• Communication: Able to communicate clearly in writing and verbally across scientific and non-scientific stakeholders; limited formal stakeholder presentations require

d in Year 1.

• Vendor management: Confident in coordinating directly with instrument vendors and following up on commitments, documentation, and testin

g schedules.

• Problem-solving mindset: Takes initiative to identify and resolve implementation issues with a practical, execution-fir

st approach.

Exper

ience Profile

• Minimum 5–8 years of experience in an analytical chemistry, lab automation, or pharmaceutical impleme

ntation role.

• Experience in a complex, matrixed pharmaceutical or biopharmaceutical environment is more important than consulting or contrac

t experience.

• Exposure to high-throughput analytical or automated drug discovery environments is a stro

ng advantage.

• Experience in predictive synthesis or nanoscale analytical workflows is preferred but n

ot mandatory.

• Prior experience in a first-time implementation or greenfield project is highly valued — the ability to build processes as well as

follow them.

What GSK Is N

OT Looking For

• Purely bench-based analytical scientists without exposure to automation, systems integration, or cross-functional

project work.

• Resources who require a fully defined process and established SOP environment before they can operat

e effectively.

• Deep QA/regulatory specialists — while documentation is a key deliverable, this is primarily an implementation and operationalization role, not a co

mpliance role.