When our values align, there's no limit to what we can achieve.

At Parexel, we all share the same goal - to improve the world's health. From clinical trials to regulatory, consulting, and market access, every clinical development solution we provide is underpinned by something special - a deep conviction in what we do.

Each of us, no matter what we do at Parexel, contributes to the development of a therapy that ultimately will benefit a patient. We take our work personally, we do it with empathy and we're committed to making a difference.

We are looking to fill a Principal Scientist I - Open Access Liquid Chromatography Chemist position working as a full-time employee of Parexel FSP on long-term assignment onsite at one of our clients located in South San Francisco, California. This position offers full benefits, sick time, 401K, paid holidays, and paid time off. This position does not offer any sponsorship.

Responsibilities

• Operate, maintain and troubleshoot open access Waters LC-MS instruments to support discovery chemistry, as well as HTE Waters LC-MS when needed.
• Utilizes analytical method development to characterize small molecules, peptides, antibody drug conjugates and others
• Conducts purity analysis of investigational compounds by liquid chromatography (LC)
• Checks instrument performance daily, prepares mobile phases, and performs routine upkeep of walkup liquid chromatography-mass spectrometry (LC-MS) instruments
• Communicate to end-user on status of instruments. Responds to end-user repair calls for LC-MS and troubleshoots/repairs simple issues such as leaks or clogs
• Submits and coordinates repair tickets for more complex issues
• Maintains accurate documentation and records
• Assist with purity analysis of investigational compounds by liquid chromatography (LC) and high-resolution mass spectrometry experiments.
• Support Laser capture microdissection (LCM) process of Open Access instruments
• LC and LC-MS analysis of small molecule samples as needed.

Qualifications

• Master's degree in analytical chemistry or biological sciences, with at least 3 or more years of relevant and hands-on experience
• PhD in analytical chemistry or biological sciences; with 1 or more years of relevant and hands-on experience

Required Skills and Experience

• Reversed-phase high-performance liquid chromatography (RP-HPLC)
• Experience with Waters, Sciex, or Agilent LC-MS instrumentation and software
• High resolution mass spectrometry
• Strong communication and coordination skills
• Proficient with written and spoken English, is required

Desired Skills and Experience

• Strong organizational skills
• Well-developed written and oral communication capabilities

About Parexel

Parexel FSP includes the CMC Operations group. We provide pharmaceutical and biopharmaceutical companies with qualified and talented technical professionals to support the development and delivery of new therapies.

For results-driven and caring individuals who want to make a meaningful difference in the world, Parexel is trusted by life sciences companies to meet their long-term staffing needs for scientists and engineers and related professionals in discovery and development of novel therapies, keeping patients at the center of everything we do, and where an inclusive community helps you be your best, transforming any career into a life-changing achievement.

Come join us!

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EEO Disclaimer

Parexel is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to legally protected status, which in the US includes race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.