Research Scientist Molecular Characterization
PI Industries LtdJob Description
Positional Purpose
The role holder will report to team lead and contribute to the research activities of biochemical & molecular biological analysis of microbes & Biomolecules. The role holder should have been well versed in Plant Metabolomics, proteomics, Biotechnology, Induced mutagenesis, Genome editing, Plant Molecular Biology and Genomics. Bioinformatics, Nextgen Sequencing & handling of large set of data. The role holder should be able to independently manage assigned projects while also providing guidance, coaching, and oversight to team members. Manage the requirements/budgets and ensure that project schedules are met and that the work is carried out efficiently and accurately, providing regular updates to the stakeholders. A good technical knowledge on biologicals research and excellent communication skills are essential.
Key Responsibilities:
Strategic
- Support actively the philosophy, values and strategy of PI Industries.
- Contribute efficiently to the overall success of Biologicals R&D by driving innovation according to objectives and targets being set by the management team.
- Create proprietary Biomolecule library.
- Support the Team Lead in personnel development, target setting, capability building, and fostering a culture of coaching, feedback, and continuous improvement.
- Engage in internal and external forums and professional networks to stay updated and enhance expertise.
Operational
- Perform molecular biology studies such as Genomic DNA isolation, RNA isolation, Cloning, Real time PCR, Gene expression profiling.
- Conduct comprehensive biochemical analyses such as ELISA, primary metabolites profiling by HPLC and GC-MS.
- Basic knowledge of LC-MS and GC-MS for hormonal analysis and volatile compound analysis.
- Utilize bioinformatics tools such as BWA, SAMtools, GATK, LoFreq, SNVer, VipR, CRISP, and CAMBA pipeline for sequencing data analysis.
- Perform GC-MS data analysis using MetaboAnalyst and Metalign, BLAST for sequence alignment, PARSESNP and SIFT for mutation analysis, and construct phylogenetic trees and heat maps.
- Efficiently browse genes from genome browser databases, conduct statistical analyses, and manage large datasets with precision.
- Design, execute, and analyse experiments and studies related to Biomolecule research, ensuring high scientific rigor and compliance with guidelines.
- Support primary screening team by identifying microorganisms using molecular biology techniques.
- Develop protocols to cultivate microorganisms in various substrates under controlled conditions to induce or maximize the production of specific biomolecules.
- Establish and consistently implement SOPs for all methods and techniques employed by the team to ensure standardization, efficiency, and quality.
- Follow documentation standards to report results, participate in all department meetings and present robust analysis of data.
- Adhere to all safety / information security / quality norms related to research procedures.
- Ensure seamless coordination with the project manager to achieve project goals effectively.
- Drive continuous improvement by identifying, prioritizing, and implementing enhancements.
- Provide scientific expertise and guidance in product development strategies, identifying opportunities for innovation.
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