Quality Control Wet Lab Chemist

Quality Control (QC) Wet Lab Chemist — Job Profile

# Overview

A QC wet lab chemist ensures raw materials, in-process samples, and finished products meet predefined specifications through laboratory testing, documentation, and compliance with quality and safety systems. The role is common in pharmaceuticals, specialty chemicals manufacturing.

## Core Responsibilities

• Perform routine and non-routine wet chemistry tests: titrations (acid-base, redox, complexometric), pH, conductivity, viscosity, moisture (Karl Fischer), chloride/sulfate by argentometric/gravimetric, hardness, ash, loss on drying, refractive index, melting point, etc.
• Conduct instrumental analyses commonly used alongside wet chemistry: UV-Vis spectrophotometry, FTIR, TOC; often exposure to pharma/chemicals.
• Sample handling: receipt, identification, and representative sampling of raw materials, intermediates, finished product, stability, and environmental/utility samples (e.g., purified water).
• Method execution and verification: follow pharmacopeial (IP, USP, BP, EP) and validated in-house methods; assist in method transfer and robustness checks.
• Data integrity and documentation: contemporaneous recording in controlled notebooks/eLIMS, calculations, CoA generation, deviations/OOS/OOT investigations, and change controls.
• Equipment management: daily checks, calibrations, basic troubleshooting, and preventive maintenance coordination for balances, pH meters, KF titrators, burettes, ovens, muffle furnaces, viscometers, UV-Vis, FTIR.
• Quality systems: adhere to GLP, GDP, cGMP; participate in internal/external audits; implement CAPA and continuous improvement.
• Safety and housekeeping: chemical hygiene, PPE, MSDS/SDS use, waste segregation, fume hood practices, 5S.
• Cross-functional support: interface with production, QA, R&D/ADL for investigations, specification setting, and process improvements.

## Typical Day in the Lab

• Calibrate pH meter/balances; standardize titrants (e.g., NaOH, HCl, AgNO3).
• Analyze queued samples; compute results; peer review and submit for QA disposition.
• Document any abnormalities; raise incident or deviation if required.
• Maintain inventory of reagents/standards; prepare fresh reagents/standards as per SOP.
• Verify logbooks/equipment usage logs, and close the day with status updates.

## Key Skills and Competencies

• Technical: strong wet chemistry, titration theory, solution prep and standardization and uncertainty calculations, pharmacopeial methods, familiarity with UV-Vis/FTIR/KF.
• Quality and compliance: GLP, GDP, cGMP, data integrity (ALCOA+), qualification/validation basics (IQ/OQ/PQ), OOS/OOT/OOT trending, stability studies.
• Digital: LIMS/eLIMS, Excel for calculations and trending, basic instrument software.
• Soft skills: attention to detail, time management under TAT pressure, teamwork, clear documentation and communication, problem-solving during investigations.
• Safety: chemical risk assessment, handling corrosives/oxidizers/solvents, spill response, waste management.

## Educational Requirements

• BSc/MSc in Chemistry, Analytical Chemistry, or related (Biochemistry/Pharmaceutical Chemistry).
• Freshers can enter as trainee QC chemists; internships or 3–6 months industrial training are advantages.
• Certifications helpful: cGMP/GLP, data integrity, pharmacopeial methods, EHS.

## Common Tests and Methods (Wet Lab Focus)

• Titrations: acid-base (potentiometric/manual), redox (iodometry/permanganometry), complexometric (EDTA for hardness/metals), precipitation (Mohr/Volhard).
• Physical tests: pH, conductivity, specific gravity/density, viscosity (Brookfield/Ubbelohde), melting/softening point, residue on ignition/ash, loss on drying.
• Moisture: volumetric and coulometric Karl Fischer.
• Spectroscopy: UV-Vis assay/impurities, FTIR identification.
• Water/utility: pH, conductivity, TOC (often separate team), chloride/sulfate, hardness.
• Sample prep: dissolution, extraction, digestion, filtration, and proper dilution practices.

# Documentation and Compliance

• SOPs, test methods, specifications, logbooks, reagent standardization records, instrument calibration logs.
• Batch records review support; CoA issuance for release.
• Deviations/OOS/OOT handling with root cause analysis and CAPA.
• Audit readiness: traceable records, up-to-date training, controlled documents, and data integrity checks.

Pay: ₹12,000.00 - ₹13,000.00 per month

Work Location: In person