Senior Software Engineer, Applied AI
LilasciencesRole Overview
Lilasciences is hiring a Senior Software Engineer, Applied AI. This is a full-time role in Cambridge, MA USA; San Francisco. Part of Lilasciences's Backend hiring, posted 3 weeks ago. Full responsibilities, required qualifications, and the apply link are listed in the description below.
Resume Keywords to Include
Make sure these keywords appear in your resume to improve ATS scoring
Job description
Your Impact at LILA
We are seeking a Senior Software Engineer to join our Applied AI group and help build the next generation of our AI-driven scientific platform. In this role, you will design and optimize the backend systems, data pipelines, and AI integrations that power intelligent, data-driven applications. You’ll work at the intersection of backend engineering and machine learning, ensuring our platform seamlessly scales and supports cutting-edge applied AI techniques such as Retrieval-Augmented Generation (RAG), agentic AI, and large language model (LLM) integration.
This role is ideal for someone who thrives in bridging software engineering and applied AI—turning research into production-grade systems that drive real-world scientific discovery. If you are passionate about building performant, elegant systems that make AI useful and impactful, we would love to hear from you!
What You'll Be Building
- Applied AI Integration: Design and deploy backend services and data pipelines that directly support advanced AI applications, including LLMs, RAG, and agentic frameworks.
- API & Service Development: Build high-performance APIs and microservices that enable seamless integration between AI models, scientific tools, and user-facing applications.
- Data Pipeline Architecture: Architect and manage scalable pipelines capable of handling structured, unstructured, and vectorized data for AI/ML workloads.
- Database & Knowledge Systems: Implement and optimize SQL, NoSQL, and vector databases to support low-latency AI retrieval and inference workloads.
- Cloud & Infrastructure: Leverage AWS, Kubernetes, and infrastructure-as-code (Terraform/CloudFormation) to build robust, production-ready AI platforms.
- Performance & Reliability: Diagnose system bottlenecks, optimize for cost and speed, and ensure the reliability and fault-tolerance of AI-driven workflows.
- Collaboration: Partner with ML researchers, platform engineers, and scientists to translate models and algorithms into scalable, production-ready systems.
What You’ll Need to Succeed
- Educational Background: Bachelor’s or Master’s in Computer Science, Engineering, or a related field.
- Backend & Data Expertise: 7+ years of professional experience building and scaling production systems, including APIs, data pipelines, and distributed services.
- Programming Skills: Strong Python skills (FastAPI, Flask, Django), with solid experience in backend service development.
- Databases: Proven experience with SQL, NoSQL, and vector databases; skilled in schema design, indexing, and query optimization.
- Applied AI Systems: Hands-on experience integrating ML models or AI-driven workflows into production services.
- Cloud & DevOps: Proficiency with AWS, Docker/Kubernetes, CI/CD pipelines, and infrastructure-as-code.
- Communication & Problem-Solving: Ability to work cross-functionally with diverse teams and explain complex technical concepts to non-experts.
Bonus Points For
- Scientific & Data-Intensive Domains: Experience working with life sciences, materials sciences, or other research-heavy fields.
- Startup Experience: Comfort with fast-paced, iterative environments where impact and adaptability matter.
Compensation
We offer competitive base compensation with bonus potential and generous early-stage equity. Your final offer will reflect your background, expertise, and expected impact.
U.S. Benefits. Full-time U.S. employees receive a comprehensive benefits program including medical, dental, and vision coverage; employer-paid life and disability insurance; flexible time off with generous company wide holidays; paid parental leave; an educational assistance program; commuter benefits, including bike share memberships for office based employees; and a company subsidized lunch program.
International Benefits. Full-time employees outside the U.S. receive a comprehensive benefits program tailored to their region. USD salary ranges apply only to U.S.-based positions; international salaries are set to local market.
About LILA
Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves.
LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.
Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.
We’re All In
Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.
Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy.
A Note to Agencies
Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.
About Lilasciences
Lilasciences
117 other open roles at Lilasciences on TryApplyNow.
Frequently Asked Questions
How do I apply for the Senior Software Engineer, Applied AI position at Lilasciences?
Use the Apply button above to submit your application directly to Lilasciences. Most applications take less than 5 minutes if your resume and contact details are ready, and you'll be routed to the employer's official application system to finish.
Where is the Senior Software Engineer, Applied AI position at Lilasciences located?
This position is based in Cambridge, MA USA; San Francisco. Lilasciences has not indicated remote or hybrid options for this role, so candidates should plan for on-site work.
What does a Senior Software Engineer, Applied AI at Lilasciences earn?
Lilasciences has not disclosed a salary range in this posting. Many employers share specifics later in the interview process; you can also ask during a recruiter screen if compensation transparency is important to you.
When was the Senior Software Engineer, Applied AI role at Lilasciences posted?
This role was posted on June 15, 2026 (24 days ago). It's still listed as actively hiring; we re-confirm openings against the source system multiple times per day and remove closed roles.
How much experience does the Senior Software Engineer, Applied AI role at Lilasciences require?
This is a senior-level position. Most senior roles call for 5+ years of directly relevant experience. Lilasciences lists their specific requirements in the description below, so review the must-have qualifications closely before applying.
Similar Jobs
Senior Software Engineer, Operations Research
Lilasciences
Senior Software Engineer, Data
Lilasciences
Principal Software Engineer, Data
Lilasciences
Software Engineer, Infrastructure
Pylon Labs
Software Engineer, Backend, Workflow Runner
Profound
More Jobs at Lilasciences
View all →Vice President, Engineering
Lilasciences
Technical Program Manager, AI Platform
Lilasciences
Staff Software Engineer, Scientific System of Record
Lilasciences
Staff Software Engineer, Lab Software
Lilasciences
Staff / Principal Research Engineer, AI Safety, Technical Mitigations
Lilasciences
AI-powered job search
Get every job scored to your resume
Upload your resume and get jobs ranked, your resume tailored, and employee contacts found automatically.
Get started freeNo credit card to start