Role Overview
Axle Health is hiring a Bioinformatics/Data Scientist. This is a full-time role in Frederick. Part of Axle Health's Data Science hiring, posted 5 days ago. Full responsibilities, required qualifications, and the apply link are listed in the description below.
Salary Context
Salary is not disclosed in this posting. Market median for Data Science roles is $160k-$220k (based on 361 comparable listings). Many employers share specifics during the interview process or after an initial screen.
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Job description
(ID: 2025-0696)
Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).
Axle is seeking a Bioinformatics/Data Scientist to join our vibrant team at the National Institutes of Health (NIH) supporting the Standardized Organoid Model Center in Frederick, MD. The Standardized Organoid Model Center is an NIH-funded initiative dedicated to advancing organoid research through the development of validated, reproducible, and well-characterized organoid models. The center brings together interdisciplinary teams of researchers to establish standardized protocols, develop quality control measures, and create resources that will benefit the broader organoid research community.
Benefits We Offer:
- 100% Medical, Dental & Vision Coverage for Employees
- Paid Time Off and Paid Holidays
- 401K match up to 5%
- Educational Benefits for Career Growth
- Employee Referral Bonus
- Flexible Spending Accounts:
- Healthcare (FSA)
- Parking Reimbursement Account (PRK)
- Dependent Care Assistant Program (DCAP)
- Transportation Reimbursement Account (TRN)
Overview
The Bioinformatics/Data Scientist will conduct comprehensive analyses of multi-omics data generated from organoid systems and corresponding normal tissues. This position is central to the SOM Center's research objectives, focusing on characterizing organoid fidelity, identifying biomarkers of successful differentiation, and developing computational frameworks for organoid quality assessment.
Responsibilities
- The successful candidate will analyze complex datasets including single-cell RNA sequencing, bulk RNA sequencing, proteomics, and metabolomics data from various organoid systems and their tissue counterparts.
- The position will develop and implement computational pipelines for data processing, quality control, and statistical analysis.
- A major component of the role involves integrating SOM-generated data with publicly available datasets to benchmark organoid characteristics against normal tissue profiles.
- The position requires close collaboration with experimental teams to interpret results and guide protocol optimization, as well as contributing to manuscript preparation and presenting findings at scientific conferences.
Required Qualifications
- Candidates must hold a PhD in bioinformatics, computational biology, biostatistics, or a related quantitative field.
- Extensive experience with single-cell data analysis, including familiarity with tools such as Seurat, Scanpy, or similar platforms, is essential.
- Strong programming skills in R and Python are required, along with experience in statistical analysis and data visualization.
- Knowledge of proteomics and metabolomics data analysis workflows is necessary.
Preferred Qualifications
- Previous experience analyzing organoid datasets is strongly preferred.
- Experience with machine learning approaches for biological data, familiarity with pathway analysis tools, and knowledge of developmental biology principles will be considered valuable assets.
- Experience with high-performance computing environments and version control systems is desirable.
Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.
The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.
Accessibility: If you need an accommodation as part of the employment process please contact: careers@axleinfo.com
This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.
#INDPSD #IND
About Axle Health

Axle Health
axlehealth.com
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Frequently Asked Questions
How do I apply for the Bioinformatics/Data Scientist position at Axle Health?
Use the Apply button above to submit your application directly to Axle Health. Most applications take less than 5 minutes if your resume and contact details are ready, and you'll be routed to the employer's official application system to finish.
Where is the Bioinformatics/Data Scientist position at Axle Health located?
This position is based in Frederick. Axle Health has not indicated remote or hybrid options for this role, so candidates should plan for on-site work.
What does a Bioinformatics/Data Scientist at Axle Health earn?
Axle Health has not disclosed a salary range in this posting. Many employers share specifics later in the interview process; you can also ask during a recruiter screen if compensation transparency is important to you.
When was the Bioinformatics/Data Scientist role at Axle Health posted?
This role was posted on July 17, 2026 (5 days ago). It's still listed as actively hiring; we re-confirm openings against the source system multiple times per day and remove closed roles.
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