The Manager, IT & Cybersecurity will lead day-to-day corporate IT operations and cybersecurity execution, ensuring reliable, secure, and scalable technology services for the business. Reporting to the CFO this role manages operational priorities, drives continuous improvement, and partners across functions to align technology support with organizational needs.

This individual will work closely with the Managed Service Provider (MSP), oversee end‑user computing tools including M365, laptops, AV systems, and security infrastructure, and serve as a trusted partner to teams across Lexeo. The ideal candidate thrives in a fast‑paced, growing biotechnology environment and is equally comfortable troubleshooting immediate issues and implementing process improvements, including the responsible use of AI to optimize ticket triage/knowledge management and accelerate issue resolution, that support future growth.

Primary Responsibilities

• Manage the day‑to‑day relationship and performance of the MSP to ensure delivery of high‑quality, cost‑effective IT services
• Coordinate IT equipment provisioning and maintenance for employees and contractors, including laptops, printers, and communication tools
• Ensure effective IT service desk operations, user lifecycle workflows, and asset and license management
• Provide direct technical support as needed to employees and consultants across the organization
• Deliver IT and cybersecurity training and communicate updates, best practices, and process improvements
• Perform regular account and access audits and ensure enforcement of least‑privilege principles
• Manage monitoring, maintenance, and support of security tools, systems, and service provider relationships
• Support development and continuous improvement of documentation, procedures, and the information security program
• Partner with cross‑functional teams to identify opportunities for automation, optimization, and efficiency
• Stay current on emerging technologies, cybersecurity risks, and industry best practices to make informed recommendations

Required Skills & Qualifications

• At least 6 years of experience in IT operations, including hands‑on leadership in a growing organization
• Minimum of 3 years of experience in the biotechnology or pharmaceutical industry
• Strong expertise in Microsoft technologies, M365, and PC environments
• Solid understanding of cybersecurity principles, data privacy standards, and compliance frameworks
• Experience managing IT projects and implementing infrastructure across diverse technologies
• Proficiency in systems administration, networking, security tools, databases, storage systems, and communication technologies
• Demonstrated ability to optimize support systems and workflows including use of responsible AI capabilities
• Strong critical thinking, decision‑making, and prioritization skills
• Service‑oriented mindset with excellent interpersonal, verbal, and written communication abilities

About Lexeo

Lexeo Therapeutics is a clinical-stage genetic medicine company headquartered in New York City, pioneering cardiac genetic medicine candidates to treat the root causes of inherited cardiovascular diseases. Our lead program, LX2006, targets cardiomyopathy associated with Friedreich’s Ataxia and anchors a broader pipeline addressing genetically defined conditions such as hypertrophic and arrhythmogenic cardiomyopathies. Backed by a strong financial foundation, Lexeo is positioned to translate groundbreaking science into durable clinical impact.

Our work culture is a hybrid model with 2 days/week in the New York City office and 3 days working from home.

Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.