QC and Research Assistant

As an In Vitro ADME Studies expert, your role involves conducting various in vitro ADME experiments and bioanalysis to support drug discovery processes. Your key responsibilities include:

• Reading and understanding various in vitro ADME protocols.
• Conducting in vitro stability experiments for new chemical entities, including liver microsomes, plasma, and other relevant matrices.
• Performing in vitro ADME experiments such as logP, logD, pKa measurements, CYP induction and inhibition assays, permeability determinations in relevant cell lines, CYP phenotyping, and solubility determinations.
• Developing and validating LC-MS/MS and HPLC-UV/PDA methods for in vitro sample analysis.
• Extracting data from instruments, conducting bioanalytical QC, and sharing reports with DMPK stakeholders.
• Analyzing bioanalytical data, calculating in vitro results using Excel, and generating reports in Excel, Word, and PowerPoint format.
• Maintaining and troubleshooting general LC-MS/MS and HPLC instruments.

Additional details of the company were not provided in the job description.

Qualifications required for this role include:

• Education: M.Sc / M.Pharm
• Experience: 2-6 years in a drug discovery industry/CRO in the DMPK department

Your expertise in in vitro ADME studies and bioanalysis will be crucial in contributing to the drug discovery processes and supporting the DMPK department's goals. As an In Vitro ADME Studies expert, your role involves conducting various in vitro ADME experiments and bioanalysis to support drug discovery processes. Your key responsibilities include:

• Reading and understanding various in vitro ADME protocols.
• Conducting in vitro stability experiments for new chemical entities, including liver microsomes, plasma, and other relevant matrices.
• Performing in vitro ADME experiments such as logP, logD, pKa measurements, CYP induction and inhibition assays, permeability determinations in relevant cell lines, CYP phenotyping, and solubility determinations.
• Developing and validating LC-MS/MS and HPLC-UV/PDA methods for in vitro sample analysis.
• Extracting data from instruments, conducting bioanalytical QC, and sharing reports with DMPK stakeholders.
• Analyzing bioanalytical data, calculating in vitro results using Excel, and generating reports in Excel, Word, and PowerPoint format.
• Maintaining and troubleshooting general LC-MS/MS and HPLC instruments.

Additional details of the company were not provided in the job description.

Qualifications required for this role include:

• Education: M.Sc / M.Pharm
• Experience: 2-6 years in a drug discovery industry/CRO in the DMPK department

Your expertise in in vitro ADME studies and bioanalysis will be crucial in contributing to the drug discovery processes and supporting the DMPK department's goals.