Role Overview
Genentech is hiring a Machine Learning Engineer/Senior Machine Learning Engineer, Infrastructure. This is a full-time role in New York, New York. Part of Genentech's Data Science hiring. The posted range is $148k to $274k. Full responsibilities, required qualifications, and the apply link are listed in the description below.
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Job Description
A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.
Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche’s Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The new Computational Sciences Center of Excellence (CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.
The Opportunity
At Roche's AI for Drug Discovery (AIDD) group (Prescient Design), we are revolutionizing drug discovery with cutting-edge machine learning techniques. We are seeking a highly motivated and skilled ML Engineer to join our growing team within Genentech Research and Early Development AI Drug Development (gRED AIDD). This role is crucial for enhancing the core features that power our machine learning initiatives. The ideal candidate will have deep experience building scalable software and infrastructure, while consistently adhering to corporate standards and best practices.
What you'll do
Machine Learning Engineer - Infra
- Design, implement, and maintain scalable and reliable ML infrastructure
- Collaborate closely with ML engineers and data scientists to understand and address their infrastructure needs.
- Document infrastructure designs, processes, and operational procedures.
Senior Machine Learning Engineer - Infra
- Design, implement, and maintain scalable and reliable ML infrastructure, leading the architecture and delivery of significant technical solutions.
- Proactively identify and solve complex, often cross-functional, technical problems within the ML infrastructure domain.
- Collaborate closely with ML engineers and data scientists to understand and address their infrastructure needs.
- Document infrastructure designs, processes, and operational procedures.
- Mentor junior engineers and drive technical alignment and influence across teams.
Who you are
Machine Learning Engineer - Infra
- BS/MS with 2-3 years of industry experience required
- Proven experience designing, deploying, and managing infrastructure on AWS (EC2, S3, RDS, etc.).
- Proficiency in scripting languages (e.g., Python) and compiled languages (e.g., C++, Go, Rust).
- Strong experience with Git and repository management.
- Excellent problem-solving skills and a proactive attitude, with the ability to anticipate needs and drive projects to completion.
- Strong communication and interpersonal skills to effectively collaborate with cross-functional teams and influence technical decisions.
- Ability to thrive in a fast-paced environment and adapt to evolving requirements while adhering to corporate guidelines.
Senior Machine Learning Engineer - Infra
- BS/MS with 3-5 years of industry experience required
- Proven experience designing, deploying, and managing infrastructure on AWS (EC2, S3, RDS, etc.).
- Proficiency in scripting languages (e.g., Python) and compiled languages (e.g., C++, Go, Rust).
- Strong experience with Git and repository management.
- Demonstrated ability to lead technical projects from conception to completion and deliver high-quality, scalable, and reliable software.
- Excellent problem-solving skills and a proactive attitude, with the ability to anticipate needs and drive projects to completion.
- Strong communication and interpersonal skills to effectively collaborate with cross-functional teams and influence technical decisions.
- Ability to thrive in a fast-paced environment and adapt to evolving requirements while adhering to corporate guidelines.
Preferred
- Extensive experience with large-scale ML model platforms and tools.
- Deep understanding and experience with PyTorch implementation, especially regarding scaling inference performance.
- A history of significant contributions to open-source projects or industry standards.
Relocation benefits are available for this job posting
The expected salary range for this position based on the primary location of California for the Machine Learning Engineer is $147,600, - $274,000 and New York is $141,100 - $262,100, and the Senior Machine Learning Engineer for California is $167,400 - $310,800 and New York is $160,100 - $297,300. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
Benefits
#ComputationCoE
#tech4lifeComputationalScience
#tech4lifeAI
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
Frequently Asked Questions
How do I apply for the Machine Learning Engineer/Senior Machine Learning Engineer, Infrastructure position at Genentech?
Use the Apply button above to submit your application directly to Genentech. Most applications take less than 5 minutes if your resume and contact details are ready, and you'll be routed to the employer's official application system to finish.
Where is the Machine Learning Engineer/Senior Machine Learning Engineer, Infrastructure position at Genentech located?
This position is based in New York, New York. Genentech has not indicated remote or hybrid options for this role, so candidates should plan for on-site work.
How much does the Machine Learning Engineer/Senior Machine Learning Engineer, Infrastructure role at Genentech pay?
Genentech has posted a compensation range of $148k to $274k for this position. Final offers typically vary based on candidate experience, location, and internal salary bands.
When was the Machine Learning Engineer/Senior Machine Learning Engineer, Infrastructure role at Genentech posted?
This role was posted on March 20, 2026 (80 days ago). It's still listed as actively hiring; we re-confirm openings against the source system multiple times per day and remove closed roles.
How much experience does the Machine Learning Engineer/Senior Machine Learning Engineer, Infrastructure role at Genentech require?
This is a senior-level position. Most senior roles call for 5+ years of directly relevant experience. Genentech lists their specific requirements in the description below, so review the must-have qualifications closely before applying.
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