Senior Director, Marketing Excellence

Amylyx Pharmaceuticals, Inc. - Common Stock

Full Timesenior

Cambridge, MAPosted January 26, 2026

Job Description

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.

The Opportunity

The Senior Director, Marketing Excellence will play a pivotal role in shaping Amylyx’s commercial strategy and driving seamless, integrated engagement across all customer touchpoints. This leader will be responsible for designing and executing a comprehensive, enterprise-wide omnichannel vision that connects with healthcare professionals and community members (patients and caregivers) through personalized, high-impact experiences. This role will integrate digital and traditional channels, leverage data-driven insights, and collaborate across functions to ensure alignment with brand objectives and launch plans. As a key strategic leader, you will shape how Amylyx engages customers, driving innovation and measurable impact. This role will also lead Marketing Operations with a focus on excellence across all aspects of Marketing.

This is a unique opportunity for a strategic, forward-thinking marketer to define how Amylyx leverages technology, analytics, and creative storytelling to deliver consistent, high-value engagement. By combining strategic insight with flawless execution, this individual will help position Amylyx as a leader in omnichannel excellence within the life sciences industry.

Responsibilities

Lead the enterprise-wide digital and omnichannel vision for Amylyx, establishing the standards, principles, and operating model that guide customer engagement and other key audience across all channels.

Develop and execute an integrated omnichannel marketing capability and strategy aligned with brand objectives and launch timelines, supported by a robust digital customer engagement capability roadmap.

Define and optimize end-to-end customer journeys for HCPs and community members to ensure personalized, consistent experiences across personal and nonpersonal touchpoints, overseeing campaign execution across CRM, marketing automation platforms, and third-party media.

Partner with brand teams to advise on the creation of compelling, compliant, audience-appropriate content while ensuring alignment with regulatory requirements.

Collaborate cross functionally with Commercial, Medical Affairs, and Corporate Communications to ensure seamless integration and synergy across all customer-facing activities.

Establish measurement frameworks with KPIs and dashboards to monitor engagement, conversion, and ROI, partnering closely with IT and analytics teams to ensure the data infrastructure supports real-time optimization.All jobs at Amylyx Pharmaceuticals, Inc. - Common Stock →